PHOSPHATASES OF RAT LIVER
نویسندگان
چکیده
منابع مشابه
Phosphatases of Rat Liver
In the dephosphorylation of ATP’ by adult rat liver homogenates, a major role is played by a magnesium-stimulated ATPase localized in the isolated mitochondrial fraction (1). However, in liver tumors, as in other tumors tested, ATP dephosphorylation is catalyzed mostly by an apyrase, stimulated equally by calcium and magnesium ions and localized in the isolated microsome fraction (2, 3). It see...
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Because the liver carries out such a large number of important syntheses, it seems very.desirable to study the synthetic processes of this organ in vitro. However, there is considerable uncertainty in such studies because of the “notorious liver phosphatases,” which presumably could interfere with syntheses by breaking down ATP’ or any phosphorylated intermediates. In order to ascertain, if pos...
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When the crude phosphoprotein phosphatase fraction of rat liver cytosol was treated with 80% aqueous ethanol at room temperature, the activity with phosphorylase alpha as substrate was increased by 110%, but those with glycogen synthase D and phosphohistone were decreased by 53 and 34%, respectively. Chromatography of the ethanol-treated fraction on DE-52 revealed that while phosphoprotein phos...
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Glucose-6-phosphatase and fructose 1,6-diphosphatase activity per 100 gm. body weight was shown to be markedly increased in the liver cells of rats bearing two strains of leukemia (J and 302) when compared with normal animals. No differences in liver succinic acid dehydrogenase activity could be demonstrated between normal, J, and 302 leukemic animals. Leukemic animals failed to give an additio...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1953
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)52336-5